What Is CJC-1295? A Guide to the GHRH Analogue

CJC-1295 is a synthetic analogue of growth hormone-releasing hormone (GHRH). This guide explains what it is, how the DAC and no-DAC versions differ, and what research examines.

CJC-1295 belongs to the family of peptides that act on the growth hormone pathway, and it is one of the most researched members of that group. This guide covers what it is, how its two main versions differ, and what investigators have looked at.

Key points

  • CJC-1295 is an analogue of GHRH (growth hormone-releasing hormone).
  • Research examines its relationship with the growth hormone axis and IGF-1.
  • It exists in two main versions: with DAC (long-acting) and without DAC, also called Mod GRF 1-29 (short-acting).
  • It is frequently studied alongside Ipamorelin, which acts through a different pathway.

What is CJC-1295?

CJC-1295 is a synthetic analogue of GHRH, the hormone that signals the release of growth hormone. In research settings it is studied for its influence on the growth hormone axis and on IGF-1.

With DAC and without DAC

Two principal versions are available:

  • With DAC — a molecular addition that considerably lengthens the molecule’s duration of activity, giving it a long half-life.
  • Without DAC (also known as Mod GRF 1-29) — a shorter, more time-limited period of activity.

Which version is used is a central question in study design, because it shapes the character of the release “pulses”. Our CJC-1295 DAC vs no-DAC guide explains the distinction in more depth.

Why it is often paired with Ipamorelin

CJC-1295 is commonly examined together with Ipamorelin because the two act on separate, complementary pathways. We cover the pairing in our dedicated article on CJC-1295 and Ipamorelin.

Frequently asked questions

What is the practical difference between the DAC and no-DAC versions?

Principally the duration of activity. The longer-acting DAC form and the shorter Mod GRF 1-29 suit different research questions.

In what form is it supplied?

As a powder, which is usually reconstituted in the laboratory with bacteriostatic water. For the arithmetic, see our peptide calculator.

Where are the product details?

See CJC-1295 with DAC and CJC-1295 + Ipamorelin. For an introduction to the wider field, read our guide to peptides.

Research use only

All Evil Peptides products are supplied strictly as reference materials for laboratory research. They are not medicines, are not intended for human or veterinary use, and nothing in this article should be read as medical advice or as a claim about effects in people.

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