NAD+ is one of the most frequently discussed molecules in research on cellular energy and ageing. Strictly speaking, it is not a peptide at all but a coenzyme. This guide explains what NAD+ is, why it is studied alongside peptides and what the research actually looks at.
Key points
- NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell.
- It plays a central role in redox reactions that underpin cellular energy production.
- NAD+ levels decline with age, which has made it a focus of ageing and mitochondrial research.
- Much of the research is still developing; NAD+ is supplied here for research use only.
What is NAD+?
Nicotinamide adenine dinucleotide, usually shortened to NAD+, is a coenzyme found throughout the body’s cells. Its main job is in energy metabolism, where it takes part in oxidation–reduction (redox) reactions that drive the production of cellular energy. It is a nucleotide derivative rather than a chain of amino acids, so it is not a peptide, although it is often discussed in the same context of cellular function.
What does the research examine?
Because NAD+ levels are known to fall with age, the molecule has been investigated in studies of ageing, mitochondrial function and associated cellular pathways, including the sirtuin family of enzymes. It is now one of the most widely discussed topics in longevity research.
Why so much attention?
The link between NAD+, cellular energy and the biology of ageing has made it a popular subject of investigation. It is worth remembering, however, that a great deal of this research is still at an early stage, and conclusions should be drawn cautiously.
Handling in the laboratory
NAD+ is supplied as a powder and is reconstituted for laboratory work using bacteriostatic water. Our reconstitution calculator helps with working out concentrations.
Frequently asked questions
Is NAD+ a peptide?
No. It is a coenzyme derived from nucleotides. It is simply studied and supplied within the broader field of cellular-function and ageing research, which is why it often appears alongside peptides such as MOTS-c.
Further reading
For specifications, visit the NAD+ research product page. For background on the wider field, read our introductory guide to research peptides.
Research use only
This article is for general educational purposes and is not medical advice. All Evil Peptides products are research reference materials for laboratory use only. They are not medicines and are not for human or veterinary consumption.